| ORIGINAL ARTICLE |
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| Year : 2021 | Volume
: 8
| Issue : 4 | Page : 267-273 |
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Risk factors for mortality in hospitalized moderate-to-severe COVID-19 patients: A single-center retrospective study
Leyla Bahadorizadeh1
 , Soheil Rahmani Fard2, Arman Karimi Behnagh3, Seyed Ali Hashemi Kiapey3, Seyed Hassan Saneii4, Sara Minaeian2
1 Antimicrobial Resistance Research Center, Institute of Immunology and Infectious Diseases; Firoozabadi Clinical Research Development Unit (FACRDU), Iran University of Medical Sciences, Tehran, Iran
2 Antimicrobial Resistance Research Center, Institute of Immunology and Infectious Diseases, Iran University of Medical Sciences, Tehran, Iran
3 Firoozabadi Clinical Research Development Unit (FACRDU); Department of Internal Medicine, School of Medicine, Iran University of Medical sciences, Tehran, Iran
4 Department of Basic Sciences of Rehabilitation, Rehabilitation Research Center, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran
Correspondence Address:
Dr. Sara Minaeian
Antimicrobial Resistance Research Center, Institute of Immunology and Infectious Diseases, Floor 3, Building no. 3, Hazrat-e Rasool General Hospital, Niyayesh St, Sattar Khan St, 1445613131, Tehran
Iran
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/iahs.iahs_66_21
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Aims: The aim of this study was to determine the mortality risk factors of hospitalized moderate-to-severe coronavirus disease 2019 (COVID-19) patients in Tehran. Materials and Methods: We retrospectively evaluated the baseline characteristics and clinical and paraclinical parameters of 223 deceased and discharged patients who were hospitalized in Firoozabadi General Hospital between March 1 and April 1, 2020. Results: According to our multiple logistic regression model, advanced age (odds ratio [OR], 1.06; 95% confidence interval [CI], 1.02–1.09; P < 0.01), reduced oxygen saturation (OR, 0.92; 95% CI, 0.87–0.96; P < 0.01), and hypertension (OR, 2.59; 95% CI, 1.04–6.46; P = 0.04) can be perceived as independent risk factors for mortality. Conclusion: Our results suggest that patients with older age, lower oxygen saturation, and hypertension are predisposed to an increased risk of mortality. Thus, to lower the COVID-19 mortality rates, patients with these characteristics should be the primary targets for early treatment, vaccination, or monitoring strategies.
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